Reverse Type 2 Diabetes

Posted by M ws On Wednesday, December 4, 2013 2 comments
A Malaysian endocrinologist, Dr Lim Ee Lin, is part of a clinical research team at Newcastle University which has discovered that Type 2 diabetes can be reversed by an extreme low calorie diet alone.
Dr Lim, who graduated from Newcastle University Medical School in 2000 and completed her specialty training in Endocrinology and Diabetes earlier this year, carried out the study as part of her postgraduate doctoral degree is working with the team led by Professor Roy Taylor.

“To have people free of diabetes after years with the condition is remarkable and all because of an eight week diet, which also regains the body’s ability to make insulin, ” said Dr. Lim.

Currently an estimated 1.4 million Malaysians, or one in six adults above the age of 30, have diabetes. Of those, 98% have Type 2 diabetes, which is a long-term condition caused by too much glucose – a type of sugar – in the blood.

In an early stage clinical trial of 11 people, all reversed their diabetes by drastically cutting their food intake to just 600 calories a day for two months and three months later, seven remained free of diabetes.

“This is a radical change in understanding Type 2 diabetes. It will change how we can explain it to people newly diagnosed with the condition. While it has long been believed that someone with Type 2 diabetes will always have the disease and that it will steadily get worse, we have shown that we can now reverse the condition,” said Dr. Lim.

Traditionally, it had been thought that as a progressive condition, Type 2 diabetes can be controlled by diet initially then tablets, but would eventually require insulin injections; and the findings of the Newcastle University team now provides a news perspective to treating it.

Type 2 diabetes, which was once known as adult-onset diabetes, is now also found in young adults and children as a result of the pancreas not producing enough insulin to break down excessive glucose or due to the body not reacting to the hormone, known as insulin sensitivity.

Thanks to Mr LYK for sharing this.

2 comments to Reverse Type 2 Diabetes

  1. says:

    Gem Two observations:
    1. Diabetes in children and young adults is Type 1.
    2. A sample size of 11 patients seems rather small for the results to be conclusive.

  1. says:

    M ws Thanks, Gem.

    I believe for clnical research, sample size requirements are different from that of survey techniques.

    There are some who argue that when the clinical context does not provide a sufficient number of research participants for a trial with adequate statistical power but the research question has great clinical significance, research can still proceed under certain conditions.

    Small clinical trials might be warranted for the study of rare diseases, unique study populations (e.g., astronauts), individually tailored therapies, in environments that are isolated, in emergency situations, and in instances of public health urgency.

    Properly designed trials with small sample sizes may provide substantial evidence of efficacy and are especially appropriate in particular situations.

    However, the conclusions derived from such studies may require careful consideration of the assumptions and inferences, given the small number of paticipants.

    Bearing in mind the statistical power, precision, and validity limitations of trials with small sample sizes, there are innovative design and analysis approaches that can improve the quality of such trials.


    Take care and thanks so much for sharing and reading with a powerful analytical mind.

    God bless and catch up again soon!


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